Conditions Chronic kidney disease

The kidneys are vital organs: they clean the blood and affect many bodily functions. Some conditions can temporarily reduce renal function. An enlarged prostate or kidney stones may cause a build-up of urine in the kidney. Circulatory failure temporarily reduces kidney performance.

Chronic kidney disease is diagnosed when the kidneys have not been working effectively for more than three months or have suffered permanent damage. The most common causes of the condition in adults are diabetes mellitus and high blood pressure.

Chronic kidney disease is particularly prevalent in older people. The condition often goes unnoticed for long periods because a decline in renal function does not initially cause any symptoms.

Chronic kidney disease is often only identified when it is already advanced. Since the body does not eliminate sufficient water, waste products of metabolism slowly accumulate, leading to symptoms.

Symptoms may present all over the body, for example:

• swelling (edema), for instance of the legs or face
• nausea, vomiting, diarrhea
• loss of appetite, weight loss
• pallor, itching
• fatigue, apathy, debility
• difficulties concentrating, confusion, impaired consciousness or even loss of consciousness
• paralysis, muscle cramps
• dyspnea (shortness of breath)

Most cases of chronic kidney disease in adults are caused by diabetes mellitus and high blood pressure.

The kidneys may also suffer permanent damage if:

• the renal tissue becomes inflamed.
• medication, particularly painkillers, is taken over the long term.
• kidney stones, tumors or scarring interfere with the flow of urine.
• congenital kidney diseases are present, such as polycystic kidney disease.

Around 9 million people in Germany have chronic kidney disease. Most are over 60 years old.

Experts estimate that approximately 100,000 people currently have kidney disease that has progressed to the point where they require dialysis – and that this figure will rise in the coming years. In addition, around 2,000 donor kidneys are transplanted annually.

Almost 27,000 people die each year in Germany from complications of chronic kidney disease.

Although renal function is already impaired at the early stage of the disease, the kidneys can still purify the blood sufficiently well. This may continue to be the case for years, and in rare cases the kidneys even recover.

However it may also happen that renal function steadily deteriorates, ending in renal insufficiency. This may progress to complete (terminal) renal failure, which is life-threatening.

More information about the various stages of kidney disease can be found at gesundheitsinformation.de.

Chronic kidney disease can be caused by diabetes mellitus and high blood pressure. So it is a good idea to reduce the risk of these conditions. To achieve this, it is important to get enough exercise, eat a healthy diet, avoid smoking, and prevent overweight as much as possible.

People who already have diabetes or high blood pressure will often require additional medication. The goal is to manage blood sugar and blood pressure effectively and prevent complications such as kidney disease as far as possible.

Doctors can diagnose the causes and severity of chronic kidney disease by performing:

• a detailed medical history (anamnesis).
• a physical examination including blood pressure reading.
• an ultrasound scan of the abdominal cavity and kidneys.
• blood tests: for example, to measure creatinine, blood sugar, hemoglobin levels, or blood gas analysis to measure the acid-base balance.
• a urine test, including a protein assay.

Results from these and other laboratory blood tests shed light on renal function. Doctors can use other results to find out, for example, whether the kidney disease has already caused complications, or whether diabetes mellitus is the cause.

If they are still not sure, scans such as computed tomography (CT) or a kidney biopsy (where a sample of tissue is taken from the kidney) may be advisable.

People with diabetes mellitus or high blood pressure are at a higher risk of chronic kidney disease. People who are at a higher risk should have their kidneys examined regularly by their doctor. This allows renal insufficiency to be detected at the early stages. 

Under the Check-up 35 program, anyone over 35 covered by statutory health insurance are entitled to a free screening checkup every three years. The goal of the checkup is to detect signs of cardiovascular disease, diabetes and kidney disease at an early stage.

The progression of the disease can be halted or slowed down if the kidneys are still working more or less normally. This is mainly achieved through medication to lower the blood pressure and prevent cardiovascular disease. It is important for people with diabetes to check their blood sugar levels.

Other medication can help with complications such as anemia or metabolic bone disease, for example products containing iron, agents stimulating blood formation (erythropoiesis) or phosphate binders. Diuretics may also be necessary. Bicarbonate of soda is used to restore the acid/base balance.

It is also important for those affected to adapt their dietary habits to the stage of the kidney disease, control the amount they drink and exercise.

Dialysis or a kidney transplant are options for treating terminal renal failure. At least one of these treatments will usually be used, although some people consciously decide not to avail of either option. Palliative treatment is advisable when it is clear that a person will die soon. It helps to achieve an end of life that is as free of suffering as possible.

More detailed information on dialysis can be found at gesundheitsinformation.de.

Detailed information on kidney transplants is available on the Federal Institute for Public Health (BIÖG) website.

Chronic kidney disease affects people’s everyday lives. Those affected have to follow specific advice, particularly in relation to eating and drinking. Specialist dietary advice is usually accessible to those with renal problems and their family members. Many renal specialists offer this type of advice.

Patients receiving dialysis should normally ensure they do not drink too much. Since the kidneys cannot operate at full capacity they frequently eliminate almost no water, causing water retention. Sucking on a lemon segment, chewing sugar-free gum or a sour sweet can help alleviate thirst.

It is also helpful to:

• avoid rooms where the air is dry,
• drink slowly,
• use small glasses and cups, and
• take medication, wherever possible, with meals instead of an extra glass of water.

People with chronic kidney disease will usually have to take several medications permanently. A medication schedule can help people to remember when to take the medication.

However there are some medicines that people should not take because their renal function is impaired, such as ibuprofen for pain. They should discuss alternatives with their doctor. Many people have to get used to entirely new treatments such as insulin injections for diabetes.

Living with chronic kidney disease can be challenging. There are restrictions on people’s diet and on how much they can drink when taking medication. Dialysis also has a huge impact on work and private life as it is so time-consuming.

In addition to a wealth of information, event announcements and initiatives related to kidney disease, the Bundesverband Niere e. V. website also lists contact details and addresses of self-help groups throughout Germany.

The prospect of most likely having to have treatment for the rest of one’s life and the restrictions this imposes, for family members as well, can be psychologically stressful and depressing. It can therefore be very helpful to talk about it with other people suffering from the same condition, either in a self-help group or during dialysis. Psychotherapy can help with severe or prolonged periods of psychological stress.