C96.5: Multifocal and unisystemic Langerhans-cell histiocytosis

You have cancer in certain immune cells.

There are various kinds of defense cells (immune cells) in the body. Specific immune cells produce antibodies in the blood. The antibodies cling to pathogens and foreign substances in the blood, for example. This allows the antibodies to make the pathogens and foreign substances visible to the immune system. The immune system helps the body to fight and eliminate diseases and foreign substances.

There are cancers of immune cells that cause serious symptoms in a short time. But there are also cancers of immune cells that are discovered accidentally and only cause a few symptoms at the beginning.

This cancer can cause bones to dissolve in certain places. The cranial bone, the pelvis and the shoulder blades, for example, are often affected. The eyes can be further forward in the eye socket than they normally are. This can cause problems with vision. You may also be very thirsty and drink large quantities. You then have to urinate often. The symptoms can be isolated and only appear in one area of the body. But sometimes you have several symptoms at the same time because lots of organs are affected by the cancer. Then one is often seriously ill. This cancer often develops in childhood.

Additional indicator

On medical documents, the ICD code is often appended by letters that indicate the diagnostic certainty or the affected side of the body.

  • G: Confirmed diagnosis
  • V: Tentative diagnosis
  • Z: Condition after
  • A: Excluded diagnosis
  • L: Left
  • R: Right
  • B: Both sides

Further information


This information is not intended for self-diagnosis and does not replace professional medical advice from a doctor. If you find an ICD code on a personal medical document, please also note the additional indicator used for diagnostic confidence.
Your doctor will assist you with any health-related questions and explain the ICD diagnosis code to you in a direct consultation if necessary.


Provided by the non-profit organization “Was hab’ ich?” gemeinnützige GmbH on behalf of the Federal Ministry of Health (BMG).