E27.1: Primary adrenocortical insufficiency

Your adrenal glands are no longer working properly.

The adrenal glands are at the top of the kidneys. The adrenal glands form the stress hormone cortisol. Cortisol has many effects in the body. For example, cortisol is important for the sugar level in the blood and for blood pressure. The adrenal glands also form a hormone that controls the amount of blood salts. Blood salts help regulate the moisture content in the body. The adrenal glands also form sex hormones. Every person has female and male sex hormones in their body.

Tissue in your adrenal gland has been damaged and destroyed. A common cause of this is the immune system. The immune system creates antibodies that attack the body’s own tissue. The adrenal gland is then no longer able to create enough messenger substances.

There may be various symptoms as a result. For example, you may lose weight, become weaker and have low blood pressure. The skin may also have a bronze discoloration. The symptoms may become more intense with stress. It is also possible that you will have no symptoms at all.

Additional indicator

On medical documents, the ICD code is often appended by letters that indicate the diagnostic certainty or the affected side of the body.

  • G: Confirmed diagnosis
  • V: Tentative diagnosis
  • Z: Condition after
  • A: Excluded diagnosis
  • L: Left
  • R: Right
  • B: Both sides

Further information


This information is not intended for self-diagnosis and does not replace professional medical advice from a doctor. If you find an ICD code on a personal medical document, please also note the additional indicator used for diagnostic confidence.
Your doctor will assist you with any health-related questions and explain the ICD diagnosis code to you in a direct consultation if necessary.


Provided by the non-profit organization “Was hab’ ich?” gemeinnützige GmbH on behalf of the Federal Ministry of Health (BMG).