D57.2: Double heterozygous sickling disorders

You have sickle cell disease. This disease means the haemoglobin in the red blood cells is not being formed correctly. This condition is congenital, which means you were born with it.

Blood is made up of a liquid part and different blood cells, among other things. The blood cells include the red blood cells, the white blood cells and the platelets. The red blood cells carry oxygen from the lungs throughout the body. Red blood cells contain the red hemoglobin that gives blood its color. This pigment is important for carrying oxygen in the blood.

Under certain conditions, sickle cell disease results in the red blood cells deforming like a sickle. The red blood cells are then less agile than usual and can particularly damage small blood vessels. If the red blood cells are broken down sooner than they normally are as a result, then you usually don’t have enough haemoglobin. Blood clots that can damage various organs can also form. The disease occurs mainly in Africa and Southeast Europe.

The disease is hereditary. Other family members may also be affected. You have also inherited another change in haemoglobin. The symptoms will depend on how the disease is inherited. A distinction is made between a mild form and a severe form. The symptoms can vary in their severity. If you have the mild form, you don’t usually have any symptoms in everyday life or only a few. However, sometimes you get symptoms with heavy physical exertion, for example. This can make you exhausted quickly or get breathless, for example. Sometimes the kidneys do not work properly and the urine can turn red.

Additional indicator

On medical documents, the ICD code is often appended by letters that indicate the diagnostic certainty or the affected side of the body.

  • G: Confirmed diagnosis
  • V: Tentative diagnosis
  • Z: Condition after
  • A: Excluded diagnosis
  • L: Left
  • R: Right
  • B: Both sides

Further information


This information is not intended for self-diagnosis and does not replace professional medical advice from a doctor. If you find an ICD code on a personal medical document, please also note the additional indicator used for diagnostic confidence.
Your doctor will assist you with any health-related questions and explain the ICD diagnosis code to you in a direct consultation if necessary.


Provided by the non-profit organization “Was hab’ ich?” gemeinnützige GmbH on behalf of the Federal Ministry of Health (BMG).