Q81.2: Epidermolysis bullosa dystrophica

You have a congenital condition where blisters form on the skin.

The skin is made up of various layers. Normally the various layers of skin hold tightly together. This condition changes the genetic make-up so that certain components of the skin cells are no longer formed properly. This results in the layers of skin not being held together so tightly. The layers of skin no longer holding together so tightly can cause various symptoms.

The condition causes blisters to form on the skin. The blisters can form, for example, on light tough, bumping, heat or without any external reason. The blisters can burst easily and then leave wounds and sores behind. There may be wounds that heal poorly. When the wounds and sores heal, the skin can look the way it did before. However, scars and areas that appear lighter or darker can also develop. Adhesions may form, too.

You can have various other symptoms. These include damaged or missing toenails or fingernails or teeth problems. Inflammation and scars can also develop in different areas of the eyes, for example. It is also possible to go blind. Some forms of the condition can also affect the moist membranes of things like the windpipe, stomach or intestines. This can cause problems with digestion, for example. You may also have brain damage or an increased risk of certain forms of skin cancer. You may also not grow properly. This condition can make you very severely ill.

This disease is hereditary. Family members can also be affected.