Primary pneumonic plague occurs due to infection with the Yersinia pestis bacterium, which is transmitted by tiny droplets in the air. The secondary form of pneumonic plague is a possible result of bubonic plague. The plague still occurs in certain areas of Africa, Asia and America, but it no longer exists in Europe.
At a glance
- Pneumonic plague is a serious bacterial infectious disease.
- It can occur on its own (primary pneumonic plague) or following bubonic plague (secondary pneumonic plague).
- With primary pneumonic plague, the infection occurs via tiny droplets in the air.
- The disease still occurs in certain areas of Africa, Asia and America.
- It no longer exists in Germany and Europe.
- The plague can be treated with antibiotics.
Note: The information in this article cannot and should not replace a medical consultation and must not be used for self-diagnosis or treatment.
What is pneumonic plague?
The plague – formerly also known as the “Black Death” – is an infectious disease caused by the bacterium Yersinia pestis. Pneumonic plague is the most serious form of the plague. It can occur on its own (primary pneumonic plague) or following bubonic plague (secondary pneumonic plague). The illness can be cured by treating it rapidly with antibiotics.
What are infectious diseases?
The video below looks at when doctors talk about an infectious disease, which pathogens trigger infectious diseases, and how they are transmitted.
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What are the symptoms of pneumonic plague?
Primary pneumonic plague is transmitted by droplets. The incubation time (between infection and the appearance of symptoms) is one to 3 days.
After infection with the bacterium, flu-like symptoms suddenly appear. The condition of an infected person deteriorates rapidly. The general symptoms are similar to those of bubonic plague. They include abnormal fatigue, headaches, vomiting, high temperature, shivering, impaired consciousness, and enlargement of the liver and spleen.
With pneumonic plague, alongside severe lung symptoms such as breathlessness, painful coughing with sputum and pain in the chest, other adverse symptoms triggered by sepsis can also appear:
- circulatory collapse
- organ failure
- blood clotting disorder with the skin turning purple
- death of tissue in the extremities
What is sepsis?
The video below explains how sepsis is triggered. What are the symptoms and how can they be treated?
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Pneumonic plague generally progresses more rapidly and is more severe than bubonic plague. If not treated it is very quickly fatal.
What causes pneumonic plague?
Pneumonic plague is caused by bacteria called Yersinia pestis. With primary pneumonic plague the infection is caused by breathing in infectious droplets.
A distinction is drawn between primary and secondary pneumonic plague. In the primary form, the germs are transmitted from a person who is ill with pneumonic plague. The secondary form is spoken of when in a patient with bubonic plague, the illness has spread to the lung. Then, too, the bacteria can be passed on in small droplets that occur when talking or sneezing. This is rare, however.
What are the risk factors for pneumonic plague?
In Germany there is no risk of catching pneumonic plague. There is a slight risk if traveling to countries and areas where there are cases of plague disease. However, it should be emphasized that this risk is actually very small. An exception is Madagascar, where there are several hundred cases of plague every year. During outbreaks of plague the risk of travelers becoming infected can increase slightly.
How common is bubonic plague?
There have been several large outbreaks of plague in Europe over the centuries: in the 6th, 13th to 15th and in the 19th century. Today’s estimates suggest that well over 100 million people have died from plague epidemics, meaning that they have been burned into the collective consciousness of humanity as great and terrible events.
Better hygiene has caused plague infections around the world to become rare, but the disease has still not been completely eradicated. A total of 3,248 cases of plague in all its forms worldwide were reported to the World Health Organization (WHO) between 2010 and 2015, with 584 infections proving fatal.
The plague is still present in certain areas of Africa, America and Asia. Almost all of those areas are in tropical and sub-tropical, i.e. in the hot and warm temperate zones roughly between 40 degrees latitude in the northern and southern hemispheres.
Madagascar has the most plague infections with several hundred cases a year. Other countries with less common cases of plague include:
- Democratic Republic of Congo
The USA is the only country outside the subtropics and tropics where the plague is present. In Germany no cases of plague have been registered over the last decades, not even by people entering the country.
Important: The risk of infection is considered low for people traveling from Germany and Europe as long as they practice good hygiene and keep away from rodents. There is a slightly greater risk in Madagascar in the period of increasing cases and outbreaks.
How does pneumonic plague progress?
Pneumonic plague is the most serious form of the plague.
The plague bacteria produce a toxic substance. If sufferers cannot be treated quickly enough, in most cases the illness is fatal within 24 hours. With pneumonic plague, in addition to general symptoms such as a high temperature, there are also specific, severe lung symptoms such as breathlessness, coughing and pain in the lung area. Breathing arrest and shock may occur.
How can a pneumonic plague infection be prevented?
There is no commonly available vaccine against the plague. If someone comes into contact with a person with plague, an antibiotic can be administered prophylactically.
The Foreign Office has published a leaflet about the plague aimed at working people and travelers who go to affected areas.
Link to the leaflet
How is pneumonic plague diagnosed?
Overall the risk of travelers from Germany and Europe getting infected is considered low in countries with isolated cases of the plague. Except for Madagascar, this applies to all countries. So the steps involved in diagnosis will only be described here for the sake of completeness.
The first indications come from questioning the person who may be ill:
- Has the person spent time in an at-risk area in recent days?
- Are any actual plague infections known of in the at-risk area?
- Has the person had contact with anyone who has the plague?
If pneumonic plague is suspected, blood or saliva samples are tested. Specific methods can be used to provide evidence of the bacteria. In Germany there are two specialized laboratories for suspected plague cases.
How is pneumonic plague treated?
Anyone who gets pneumonic plague must be taken to hospital as quickly as possible and treated with appropriate antibiotics.
Initially, and during treatment, it should be ensured that the plague bacteria have not become resistant to the drug being used.
- Auswärtiges Amt. Merkblatt für Beschäftigte und Reisende: Pest. Aufgerufen am 23.06.2020.
- European Center for Disease Prevention and Control (ECDC). Plague. Annual Epidemiologic Report for 2018. Aufgerufen am 23.06.2020.
- Robert Koch-Institut (RKI). Antworten auf häufig gestellte Fragen zu Pest. Aufgerufen am 23.06.2020.
- Robert Koch-Institut (RKI). Infektionsepidemiologisches Jahrbuch meldepflichtiger Krankheiten für 2018. Aufgerufen am 23.06.2020.
- Robert Koch-Institut (RKI). RKI-Ratgeber Pest. Aufgerufen am 23.06.2020.
- World Health Organization (WHO). Plague. Aufgerufen am 23.06.2020.
Reviewed by the German Society for Tropical Medicine, Travel Medicine and Global Health (DTG). As at: